Research Guide
GHK-Cu
Also known as: Copper Research Compound-1
The naturally occurring copper research compound for skin, hair and wound regeneration research.
Overview
GHK-Cu is a naturally occurring human plasma research compound complexed with copper. It is one of the most-studied research compounds in skin regeneration, hair follicle research and wound healing — with documented modulation of over 4,000 human genes.
Mechanism of action
GHK-Cu upregulates collagen, elastin and glycosaminoglycan synthesis while suppressing inflammatory and fibrotic gene expression. The copper ion is essential to its biological activity.
Reference range (research literature)
Subcutaneous research: 1–2mg/day. Topical research: 0.05–0.2% solutions applied to skin or scalp.
Half-life
About 30 minutes systemically, with longer tissue residence.
Reconstitution
Reconstitute the 100mg vial with 5ml bacteriostatic water. Each 0.1ml = 2mg. The solution will be blue — this is the copper-research-compound complex and is normal.
Comparisons
vs Topical retinoids
Retinoids signal cell turnover; GHK-Cu signals regeneration and matrix synthesis.
Commonly researched stacks
- BPC-157 / TB-500 (tissue repair)
Frequently asked
Why is the solution blue?
The copper-research-compound complex is naturally blue. A clear or green solution indicates degradation.
Subcutaneous or topical?
Subcutaneous targets systemic effects; topical targets skin and hair locally.
Disclaimer: Information on this page is for research and educational use only. Research compounds sold by AUSPEPS are not approved for human consumption and are intended exclusively for laboratory research.